Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 14/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14735333 | 0.86 | USP7 (0.79) | USP7 | |
| SCHEMBL14747849 | 0.85 | USP7 (0.64) | USP7ALDH1A1NPSR1TDP1GLA | |
| SCHEMBL14747843 | 0.85 | USP7 (0.64) | USP7ALDH1A1NPSR1TDP1GLA | |
| SCHEMBL14747844 | 0.85 | USP7 (0.64) | USP7ALDH1A1NPSR1TDP1GLA | |
| SCHEMBL14747848 | 0.84 | USP7 (0.62) | USP7ALDH1A1NPSR1TDP1GLA | |
| SCHEMBL14747846 | 0.83 | USP7 (0.72) | USP7ALDH1A1 | |
| SCHEMBL14747845 | 0.81 | USP7 (0.66) | USP7ALDH1A1NPSR1TDP1GLA | |
| SCHEMBL26036201 | 0.80 | USP7 (0.65) | USP7 | |
| SCHEMBL14747841 | 0.79 | USP7 (0.56) | USP7ALDH1A1NPSR1TDP1GLA | |
| SCHEMBL26035488 | 0.78 | USP7 (0.80) | USP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565186-A1 | Selective and reversible inhibitors of ubiquitin specific protease 7 | Hybrigenics S.A. (FR) | 2013-03-06 | — | — | EP | disclosed |