SCHEMBL26036201

SCHEMBL26036201

COC1(Cn2cnc3cc(Cl)ccc3c2=O)CCN(C(=O)Cc2ccccc2)CC1

nearest known ligand 0.65

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 17/20 0.65
USP19 O94966 2/20 0.46
MEN1 O00255 1/20 0.42
GPR183 P32249 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30063698 0.87 USP7 (0.83) USP7
SCHEMBL20864300 0.87 USP7 (0.83) USP7
SCHEMBL26036413 0.87 USP7 (0.57) USP7USP19
SCHEMBL26036207 0.86 USP7 (0.80) USP7
SCHEMBL26036212 0.86 USP7 (0.80) USP7
SCHEMBL26036285 0.83 USP7 (0.52) USP7GPR183
SCHEMBL26036429 0.82 USP7 (0.55) USP7USP19MEN1KMT2A
SCHEMBL26036424 0.80 USP7 (0.53) USP7USP19
SCHEMBL14747840 0.80 USP7 (0.61) USP7
SCHEMBL14735116 0.79 USP7 (1.00) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265070-A1 NOVEL USP7 INHIBITORS FOR TREATING MULTIPLE MYELOMA DANA-FARBER CANCER INSTITUTE, INC. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265070-A1 NOVEL USP7 INHIBITORS FOR TREATING MULTIPLE MYELOMA USP7, USP1, USP3 USP7 1/4885USP19 8/4885MEN1 507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.