Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912931 | 1.00 | PIN1 (0.51) | PIN1MMP8POLBALDH1A1CHRM2 | |
| SCHEMBL2910521 | 0.93 | PIN1 (0.54) | PIN1MMP8POLBALDH1A1CHRM2 | |
| SCHEMBL15973619 | 0.88 | PIN1 (0.50) | PIN1MMP8POLBALDH1A1CHRM2 | |
| Malonic Acid SCHEMBL18670143 | 0.86 | MMP8 (0.50) | PIN1MMP8POLBALDH1A1CHRM2 | |
| SCHEMBL1581080 | 0.86 | PIN1 (0.49) | PIN1MMP8POLBALDH1A1CHRM2 | |
| SCHEMBL14791242 | 0.86 | MAPT (0.50) | PIN1MMP8POLBALDH1A1CHRM2 | |
| SCHEMBL27518382 | 0.84 | KMT2A (0.43) | POLBALDH1A1CHRM2CHRM1CHRM3 | |
| SCHEMBL7427036 | 0.83 | TSHR (0.50) | POLBALDH1A1CHRM2CHRM1CHRM3 | |
| SCHEMBL15944490 | 0.83 | MMP8 (0.51) | PIN1MMP8POLBALDH1A1CHRM2 | |
| SCHEMBL3949682 | 0.83 | MAPK1 (0.46) | PIN1ALDH1A1NPSR1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565273-A1 | New malonate decarboxylases for industrial applications | BASF SE (DE) | 2013-03-06 | — | — | EP | disclosed |