Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 14/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135481 | 0.89 | MEN1 (0.66) | MEN1KMT2AOPRD1OPRM1SLC6A4 | |
| SCHEMBL4152093 | 0.84 | SLC6A4 (0.60) | MEN1KMT2AOPRD1OPRM1SLC6A4 | |
| SCHEMBL8964096 | 0.84 | OPRD1 (0.57) | MEN1KMT2AOPRD1OPRM1SLC6A4 | |
| SCHEMBL2794662 | 0.79 | MEN1 (1.00) | MEN1KMT2AOPRD1OPRM1SLC6A4 | |
| SCHEMBL219432 | 0.79 | MEN1 (1.00) | MEN1KMT2AOPRD1OPRM1SLC6A4 | |
| SCHEMBL10357009 | 0.79 | TACR1 (0.53) | MEN1KMT2AOPRD1OPRM1SLC6A4 | |
| SCHEMBL1743579 | 0.79 | MEN1 (0.72) | MEN1KMT2AOPRD1OPRM1SLC6A4 | |
| SCHEMBL7101300 | 0.79 | MEN1 (0.72) | MEN1KMT2AOPRD1OPRM1SLC6A4 | |
| SCHEMBL7098971 | 0.79 | MEN1 (0.72) | MEN1KMT2AOPRD1OPRM1SLC6A4 | |
| Hydrochloric Acid SCHEMBL5011277 | 0.77 | MEN1 (0.70) | MEN1KMT2AOPRD1OPRM1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565183-A1 | Glycine transporter-1 inhibitors | Amgen Inc. (US) | 2013-03-06 | — | — | EP | disclosed |