Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529968 | 0.86 | UCHL1 (0.45) | KMT2AMEN1UCHL1MAPTPTGS2 | |
| SCHEMBL19622305 | 0.77 | KMT2A (0.45) | KMT2AMEN1MAPTPTGS2KDM4E | |
| SCHEMBL2528859 | 0.74 | UCHL1 (0.44) | KMT2AMEN1UCHL1MAPTPTGS2 | |
| SCHEMBL11993074 | 0.74 | KMT2A (0.36) | KMT2AMEN1UCHL1MAPTLMNA | |
| SCHEMBL7488349 | 0.69 | KMT2A (0.67) | KMT2AMEN1KDM4EUSP2LMNA | |
| SCHEMBL2530561 | 0.69 | PDE4B (0.60) | — | |
| SCHEMBL18015950 | 0.69 | PDE4B (0.48) | KMT2AMEN1PTGS2 | |
| SCHEMBL8004417 | 0.68 | CA12 (0.38) | UCHL1LMNASMN1; SMN2CA12ALDH1A1 | |
| SCHEMBL2529054 | 0.67 | F10 (0.44) | UCHL1PTGS2LMNAPOLBALDH1A1 | |
| SCHEMBL5064664 | 0.67 | UCHL1 (0.43) | KMT2AMEN1UCHL1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2564857-A1 | Boron-containing small molecules as anti-inflammatory agents | Anacor Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |