Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488349 | 0.79 | KMT2A (0.67) | KMT2AMEN1USP2RAB9ANPC1 | |
| SCHEMBL2529968 | 0.79 | UCHL1 (0.45) | KMT2AMEN1MAPTUSP2RAB9A | |
| SCHEMBL14748469 | 0.77 | KMT2A (0.36) | KMT2AMEN1MAPTUSP2RAB9A | |
| SCHEMBL11994561 | 0.73 | ERN1 (0.48) | KMT2AMEN1MAPTUSP2RAB9A | |
| SCHEMBL2531277 | 0.73 | ERN1 (0.48) | KMT2AMEN1MAPTUSP2RAB9A | |
| SCHEMBL1546951 | 0.72 | KMT2A (0.57) | KMT2AMEN1MAPTUSP2RAB9A | |
| SCHEMBL9826483 | 0.72 | KMT2A (0.52) | KMT2AMEN1MAPTUSP2RAB9A | |
| SCHEMBL14748429 | 0.70 | PTGS2 (0.43) | KMT2AMEN1USP2RAB9ANPC1 | |
| SCHEMBL11833586 | 0.70 | CA12 (0.50) | KMT2AMEN1MAPTUSP2DPP4 | |
| SCHEMBL4551259 | 0.70 | HPGD (0.57) | KMT2AMEN1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246034-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | Anacor Pharmaceuticals, Inc. (US) | 2017-11-22 | — | — | EP | disclosed |