SCHEMBL14748988

SCHEMBL14748988

CC(C)[C@H](OCCN1CCC1)C(C)(C)O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PSMB1 P20618 3/20 0.39
PSMB5 P28074 3/20 0.39
PSMB2 P49721 2/20 0.39
SLC6A4 P31645 4/20 0.37
SLC6A3 Q01959 4/20 0.37
KDM4E B2RXH2 2/20 0.34
HRH3 Q9Y5N1 2/20 0.34
CHRNA7 P36544 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14748856 0.87 KDM4E (0.37) PSMB1PSMB5PSMB2SLC6A4SLC6A3
SCHEMBL12123112 0.76 PSMB1 (0.40) PSMB1PSMB5PSMB2SLC6A4SLC6A3
SCHEMBL12123117 0.73 PSMB1 (0.38) PSMB1PSMB5PSMB2SLC6A4SLC6A3
SCHEMBL10196944 0.73 PSMB1 (0.41) PSMB1PSMB5SLC6A4SLC6A3KDM4E
SCHEMBL12207087 0.71 HSD17B10 (0.33) HSD17B10
SCHEMBL14748857 0.71
SCHEMBL12233179 0.71 HSD17B10 (0.33) HSD17B10
SCHEMBL12123116 0.71 PSMB1 (0.36) PSMB1PSMB5PSMB2SLC6A4SLC6A3
SCHEMBL24856604 0.70 ALDH1A1 (0.39) PSMB1PSMB5PSMB2SLC6A4SLC6A3
SCHEMBL9081026 0.70 PSMB1 (0.42) PSMB1PSMB5PSMB2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SATORI PHARMACEUTICALS, INC. (US) 2013-03-07 US disclosed
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SATORI PHARMACEUTICALS, INC. (US) 2013-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SNCA, HTT, CLN6 PSMB1 3254/4885PSMB5 800/4885PSMB2 2467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.