SCHEMBL14749439

SCHEMBL14749439

O=C(COCCOCCOCC(=O)Oc1ccc([N+](=O)[O-])cc1)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 0.60
CTNNB1 P35222 1/20 0.60
PTPN7 P35236 1/20 0.58
PTPN12 Q05209 1/20 0.58
PTPN22 Q9Y2R2 1/20 0.58
GAA P10253 1/20 0.51
KMT2A Q03164 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
MAPT P10636 3/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
PKM P14618 1/20 0.48
MGLL Q99685 2/20 0.47
PTGS2 P35354 1/20 0.46
ALDH1A1 P00352 3/20 0.45
LMNA P02545 2/20 0.45
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
THRB P10828 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15708314 0.98 BCL9 (0.62) BCL9CTNNB1PTPN7PTPN12PTPN22
SCHEMBL25632339 0.93 KMT2A (0.59) BCL9CTNNB1PTPN7PTPN12PTPN22
SCHEMBL2577561 0.92 BCL9 (0.66) BCL9CTNNB1PTPN7PTPN12PTPN22
SCHEMBL4641510 0.92 BCL9 (0.63) BCL9CTNNB1PTPN7PTPN12PTPN22
SCHEMBL17554614 0.91 BCL9 (0.55) BCL9CTNNB1PTPN7PTPN12PTPN22
SCHEMBL4644751 0.91 BCL9 (0.58) BCL9CTNNB1PTPN7PTPN12PTPN22
SCHEMBL14749411 0.90 BCL9 (0.51) BCL9CTNNB1PTPN7PTPN12PTPN22
SCHEMBL25614106 0.89 ALDH1A1 (0.54) BCL9CTNNB1PTPN7PTPN12PTPN22
SCHEMBL803307 0.86 BCL9 (0.52) BCL9CTNNB1PTPN7PTPN12PTPN22
SCHEMBL18753017 0.86 BCL9 (0.52) BCL9CTNNB1PTPN7PTPN12PTPN22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023139145-A1 SAPONIN-BASED ADJUVANTS AND VACCINES ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) 2023-07-27 WO disclosed
EP-4190359-A1 SAPONIN-BASED ADJUVANTS AND VACCINES Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE (ES) 2023-06-07 EP disclosed
US-20130059998-A1 Poly(Ester Amide) Macromers and Polymers Thereof CORNELL UNIVERSITY 2013-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059998-A1 Poly(Ester Amide) Macromers and Polymers Thereof PAM, PARG, MAX BCL9 4275/4885CTNNB1 4655/4885PTPN7 3561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.