Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14749794 | 0.77 | TSHR (0.40) | TSHRKMT2APER2CRY2L3MBTL1 | |
| SCHEMBL14749821 | 0.71 | TSHR (0.36) | TSHRKMT2AMEN1 | |
| SCHEMBL14827917 | 0.71 | TSHR (0.36) | TSHRKMT2AMAPTSLC1A2MEN1 | |
| SCHEMBL22114356 | 0.70 | ACE (0.36) | TSHRPIK3CDPER2 | |
| SCHEMBL13693984 | 0.67 | MERTK (0.33) | TSHRKMT2AMAPTMEN1CYP1A2 | |
| SCHEMBL23802741 | 0.66 | SLC6A9 (0.38) | PIK3CDCYP1A2 | |
| SCHEMBL14749808 | 0.66 | PIK3C3 (0.33) | PIK3CD | |
| SCHEMBL23802835 | 0.63 | XIAP (0.37) | KMT2ASLC1A2MEN1CYP1A2ALOX15 | |
| SCHEMBL17234486 | 0.63 | TSHR (0.34) | TSHR | |
| SCHEMBL1636787 | 0.62 | P2RX7 (0.46) | TSHRKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013031922-A1 | PYRAZOLE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | 日本たばこ産業株式会社 (JP) | 2013-03-07 | — | — | WO | disclosed |