SCHEMBL14752452

SCHEMBL14752452

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCSSCCNC(=O)CCC

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 7/20 0.68
▸ FAAH O00519 2/20 0.58
▸ ALDH1A1 P00352 2/20 0.58
▸ CNR2 P34972 2/20 0.58
▸ MEN1 O00255 2/20 0.58
▸ KMT2A Q03164 2/20 0.58
▸ TRPM8 Q7Z2W7 1/20 0.58
▸ KCNK3 O14649 1/20 0.58
▸ BLM P54132 1/20 0.58
▸ TRPV1 Q8NER1 1/20 0.58
▸ MAPT P10636 2/20 0.57
▸ HPGD P15428 1/20 0.57
▸ ALOX12 P18054 1/20 0.57
▸ TDP1 Q9NUW8 1/20 0.57
▸ SLC6A5 Q9Y345 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12478623 0.96 CNR1 (0.73) CNR1FAAHALDH1A1CNR2MEN1
SCHEMBL12685101 0.93 CNR1 (0.69) CNR1FAAHALDH1A1CNR2MEN1
SCHEMBL14752451 0.92 CNR1 (0.68) CNR1FAAHALDH1A1CNR2MEN1
SCHEMBL14739564 0.90 CNR1 (0.66) CNR1FAAHALDH1A1CNR2MEN1
SCHEMBL14739704 0.90 CNR1 (0.66) CNR1FAAHALDH1A1CNR2MEN1
SCHEMBL1604481 0.90 CNR1 (0.66) CNR1FAAHALDH1A1CNR2MEN1
SCHEMBL14739566 0.90 CNR1 (0.66) CNR1FAAHALDH1A1CNR2MEN1
SCHEMBL14746491 0.89 CNR1 (0.64) CNR1FAAHALDH1A1CNR2MEN1
SCHEMBL14739323 0.89 CNR1 (0.64) CNR1FAAHALDH1A1MEN1KMT2A
SCHEMBL14740184 0.89 CNR1 (0.64) CNR1FAAHALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170073305-A1 FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE CATABASIS PHARMACEUTICALS, INC. 2017-03-16 — — US disclosed
US-20130059801-A1 FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE CATABASIS PHARMACEUTICALS, INC. (US) 2013-03-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059801-A1 FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE FASN, FADS1, ELOVL5 CNR1 1072/4885FAAH 29/4885ALDH1A1 810/4885
US-20170073305-A1 FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE FASN, FADS1, ELOVL5 CNR1 1072/4885FAAH 29/4885ALDH1A1 810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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