Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29921698 | 0.81 | KMT2A (0.51) | SMN1; SMN2KMT2ALMNACDK5KDM4E | |
| SCHEMBL16978930 | 0.76 | LMNA (0.48) | LRRK2SMN1; SMN2KMT2ALMNAAURKA | |
| SCHEMBL3415008 | 0.75 | PARP1 (0.38) | LMNANNMTSIRT6ADORA3TSHR | |
| SCHEMBL31226700 | 0.72 | LMNA (0.39) | SMN1; SMN2KMT2ALMNANNMTSIRT6 | |
| SCHEMBL164974 | 0.72 | LMNA (0.39) | KMT2ALMNANNMTSIRT6ADORA3 | |
| SCHEMBL11347539 | 0.70 | RAF1 (0.44) | LRRK2SMN1; SMN2KMT2AADORA3TSHR | |
| SCHEMBL29705430 | 0.70 | NNMT (0.46) | KMT2ANNMTSIRT6KDM4EMAPT | |
| SCHEMBL25692509 | 0.70 | ICAM1 (0.35) | SMN1; SMN2KMT2ALMNANNMTSIRT6 | |
| SCHEMBL27215247 | 0.70 | NNMT (0.46) | KMT2ANNMTSIRT6KDM4EMAPT | |
| SCHEMBL30364115 | 0.70 | PARP1 (0.42) | SMN1; SMN2KMT2ALMNANNMTSIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013031694-A1 | AMINE COMPOUND AND SALT THEREOF | 富山化学工業株式会社 (JP) | 2013-03-07 | — | — | WO | disclosed |