Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.42 |
| ▸ | ADH1A | P07327 | 4/20 | 0.42 |
| ▸ | ADH7 | P40394 | 3/20 | 0.42 |
| ▸ | ADH1C | P00326 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24508645 | 0.87 | ADH1B (0.46) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL24509118 | 0.77 | ADH1B (0.40) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL14756180 | 0.76 | — | — | |
| SCHEMBL12835748 | 0.74 | CYP2C19 (0.36) | ALDH1A1 | |
| SCHEMBL23011664 | 0.74 | MEN1 (0.47) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL21391476 | 0.74 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL22788871 | 0.73 | — | — | |
| SCHEMBL3628993 | 0.73 | — | — | |
| SCHEMBL10125773 | 0.73 | — | — | |
| SCHEMBL8572245 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015106292-A1 | BCR-ABL TYROSINE-KINASE LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2015-07-16 | — | — | WO | disclosed |
| WO-2013033270-A2 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |
| WO-2013033269-A1 | BIOORTHOGONAL MONOMERS CAPABLE OF DIMERIZING AND TARGETING BROMODOMAINS AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |