Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14756200 | 0.82 | TAAR1 (0.50) | NOS1NOS2MAPTTP53CYP1A2 | |
| SCHEMBL14756334 | 0.80 | TAAR1 (0.38) | MAPTTP53CYP1A2ALOX15TSHR | |
| SCHEMBL15985218 | 0.78 | MAPT (0.43) | NOS1NOS2MAPTTP53CYP1A2 | |
| SCHEMBL14756314 | 0.75 | MAPT (0.45) | NOS1NOS2MAPTTP53CYP1A2 | |
| SCHEMBL14756312 | 0.70 | NOS1 (0.49) | NOS1NOS2MAPTTP53CYP1A2 | |
| SCHEMBL24261121 | 0.70 | ALDH1A1 (0.50) | TP53CYP1A2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL14756104 | 0.69 | TAAR1 (0.49) | NOS1NOS2MAPTTP53CYP1A2 | |
| SCHEMBL15985406 | 0.69 | MAPT (0.49) | MAPTTP53CYP1A2ALOX15TSHR | |
| SCHEMBL13875037 | 0.68 | TAAR1 (0.61) | MAPTTP53CYP1A2ALOX15TSHR | |
| SCHEMBL15985420 | 0.68 | MAPT (0.44) | NOS1NOS2MAPTTP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033268-A2 | BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |