Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14756189 | 0.79 | LOXL2 (0.42) | LOXL2HDAC6F2F10PRMT1 | |
| SCHEMBL10674648 | 0.79 | LOXL2 (0.42) | LOXL2F2F10PRMT1AGXT | |
| SCHEMBL10670572 | 0.79 | LOXL2 (0.42) | LOXL2HDAC6F2F10PRMT1 | |
| SCHEMBL19601690 | 0.76 | TAAR1 (0.46) | LOXL2HDAC6F2F10PRMT1 | |
| SCHEMBL22932538 | 0.76 | LOXL2 (0.37) | LOXL2PRMT1CA2CA12CA1 | |
| SCHEMBL140395 | 0.76 | LOXL2 (0.71) | LOXL2F2F10AGXTCA2 | |
| SCHEMBL10679481 | 0.75 | HTR1D (0.40) | LOXL2HDAC6F2F10PRMT1 | |
| SCHEMBL19604095 | 0.75 | LOXL2 (0.39) | LOXL2F2F10PRMT1CA2 | |
| Iodide SCHEMBL28674174 | 0.74 | LOXL2 (0.69) | LOXL2F2F10AGXTCA2 | |
| SCHEMBL10676305 | 0.71 | KDM4E (0.40) | LOXL2CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033268-A2 | BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |