Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.64 |
| ▸ | BRD2 | P25440 | 18/20 | 0.64 |
| ▸ | BRD3 | Q15059 | 18/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15980898 | 0.80 | BRD4 (0.72) | BRD4BRD2BRD3 | |
| SCHEMBL14740758 | 0.79 | BRD4 (1.00) | BRD4BRD2BRD3 | |
| SCHEMBL15980908 | 0.77 | BRD4 (0.76) | BRD4BRD2BRD3 | |
| SCHEMBL14756381 | 0.76 | BRD4 (0.85) | BRD4BRD2BRD3 | |
| SCHEMBL14756377 | 0.76 | BRD4 (0.85) | BRD4BRD2BRD3 | |
| SCHEMBL14740769 | 0.76 | BRD4 (0.74) | BRD4BRD2BRD3 | |
| SCHEMBL15980799 | 0.74 | BRD4 (0.76) | BRD4BRD2BRD3 | |
| SCHEMBL16756674 | 0.73 | BRD4 (0.76) | BRD4BRD2BRD3 | |
| SCHEMBL12338501 | 0.71 | BRD4 (0.63) | BRD4BRD2BRD3 | |
| SCHEMBL14756326 | 0.71 | BRD4 (0.74) | BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033268-A2 | BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |