Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 1.00 |
| ▸ | BRD2 | P25440 | 18/20 | 1.00 |
| ▸ | BRD3 | Q15059 | 18/20 | 1.00 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA7 | P43166 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15980908 | 0.87 | BRD4 (0.76) | BRD4BRD2BRD3 | |
| SCHEMBL14740769 | 0.85 | BRD4 (0.74) | BRD4BRD2BRD3 | |
| SCHEMBL15980898 | 0.84 | BRD4 (0.72) | BRD4BRD2BRD3 | |
| SCHEMBL15980799 | 0.83 | BRD4 (0.76) | BRD4BRD2BRD3 | |
| SCHEMBL14756139 | 0.80 | BRD4 (0.71) | BRD4BRD2BRD3 | |
| SCHEMBL16756674 | 0.79 | BRD4 (0.76) | BRD4BRD2BRD3 | |
| SCHEMBL14757093 | 0.79 | BRD4 (0.72) | BRD4BRD2BRD3 | |
| SCHEMBL14756408 | 0.79 | BRD4 (0.64) | BRD4BRD2BRD3 | |
| SCHEMBL30269812 | 0.78 | PTGS2 (0.67) | BRD4BRD2BRD3CA1CA2 | |
| SCHEMBL14756381 | 0.78 | BRD4 (0.85) | BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033270-A2 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |