Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14758368 | 0.91 | PDGFRB (0.45) | NQO2SLC2A1PDGFRBPDGFRATLR8 | |
| SCHEMBL16217112 | 0.88 | TLR8 (0.40) | NQO2SLC2A1PDGFRBPDGFRATLR8 | |
| SCHEMBL16217091 | 0.87 | NQO2 (0.40) | NQO2SLC2A1PDGFRBPDGFRATLR8 | |
| SCHEMBL13870938 | 0.81 | NQO2 (0.46) | NQO2PDGFRBPDGFRATLR8KDM4E | |
| SCHEMBL8887931 | 0.77 | MEN1 (0.50) | NQO2PDGFRBPDGFRATLR8KDM4E | |
| SCHEMBL13870937 | 0.76 | PDGFRB (0.47) | NQO2PDGFRBPDGFRAKDM4EALDH1A1 | |
| SCHEMBL13870934 | 0.76 | PDGFRB (0.43) | NQO2PDGFRBPDGFRAKDM4EALDH1A1 | |
| SCHEMBL13870936 | 0.75 | PDGFRB (0.45) | NQO2PDGFRBPDGFRATLR8KDM4E | |
| SCHEMBL28280763 | 0.72 | EHMT2 (0.59) | NQO2SLC2A1PDGFRBPDGFRATLR8 | |
| SCHEMBL13870939 | 0.71 | KDM4E (0.55) | NQO2SLC2A1PDGFRBPDGFRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033037-A2 | NOVEL ANTIPRION COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-07 | — | — | WO | disclosed |