SCHEMBL13870936

SCHEMBL13870936

COc1cc2ccc(-c3cccc(C)c3C)nc2cc1OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 3/20 0.45
PDGFRA P16234 3/20 0.45
ALDH1A1 P00352 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 1/20 0.42
NQO2 P16083 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
NUDT1 P36639 2/20 0.40
MAPT P10636 2/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
MCHR1 Q99705 1/20 0.40
AR P10275 2/20 0.39
AMY1A P0DUB6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8887931 0.88 MEN1 (0.50) PDGFRBPDGFRAALDH1A1SMN1; SMN2NPC1
SCHEMBL16487808 0.86 CD274 (0.41) MEN1KMT2AMAOAMAOBNUDT1
SCHEMBL13870902 0.84 NUDT1 (0.44) PDGFRBALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL14500750 0.82 NCF1 (0.49) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL13870945 0.82 RAD52 (0.41) PDGFRBPDGFRAALDH1A1SMN1; SMN2NPC1
SCHEMBL13989406 0.80 ESR1 (0.48) ALDH1A1SMN1; SMN2RAB9ANQO2NUDT1
SCHEMBL13870938 0.80 NQO2 (0.46) PDGFRBPDGFRAALDH1A1SMN1; SMN2NPC1
SCHEMBL13870927 0.79 KDM4E (0.51) PDGFRBPDGFRAALDH1A1SMN1; SMN2RAB9A
SCHEMBL13298987 0.78 CYP1A2 (0.49) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL4439948 0.77 AR (0.63) ALDH1A1NPC1RAB9AKDM4ENUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IK, G6PD, EYA2 PDGFRB 1748/4885PDGFRA 1137/4885ALDH1A1 111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.