SCHEMBL13870938

SCHEMBL13870938

COc1cc2ccc(-c3cc(C)c(C)cc3C)nc2cc1OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 3/20 0.46
PDGFRB P09619 6/20 0.45
PDGFRA P16234 6/20 0.45
ALDH1A1 P00352 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
KDM4E B2RXH2 3/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
MAPT P10636 3/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
AMY1A P0DUB6 2/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
G6PD P11413 1/20 0.38
PKM P14618 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
TLR8 Q9NR97 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16487809 0.85 TAAR1 (0.36) NQO2PDGFRBPDGFRAALDH1A1SMN1; SMN2
SCHEMBL13870908 0.84 NQO2 (0.43) NQO2PDGFRBALDH1A1SMN1; SMN2KDM4E
SCHEMBL13870934 0.84 PDGFRB (0.43) NQO2PDGFRBPDGFRAALDH1A1SMN1; SMN2
SCHEMBL13870937 0.84 PDGFRB (0.47) NQO2PDGFRBPDGFRAALDH1A1SMN1; SMN2
SCHEMBL8887931 0.82 MEN1 (0.50) NQO2PDGFRBPDGFRAALDH1A1SMN1; SMN2
SCHEMBL14758552 0.81 NQO2 (0.41) NQO2PDGFRBPDGFRAALDH1A1SMN1; SMN2
SCHEMBL14500747 0.81 NCF1 (0.53) NQO2ALDH1A1SMN1; SMN2KDM4ENPC1
SCHEMBL13870947 0.80 PSMB5 (0.44) NQO2PDGFRBPDGFRAALDH1A1SMN1; SMN2
SCHEMBL13870936 0.80 PDGFRB (0.45) NQO2PDGFRBPDGFRAALDH1A1SMN1; SMN2
SCHEMBL13870939 0.79 KDM4E (0.55) NQO2PDGFRBPDGFRAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IK, G6PD, EYA2 NQO2 1945/4885PDGFRB 1748/4885PDGFRA 1137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.