Sugi Predict

Sugi Predict / Compounds / SCHEMBL1475879

SCHEMBL1475879

SCHEMBL1475879

[CH2]CCCCC#CCCCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN7 P35236 5/20 0.50
▸ HMGCR P04035 3/20 0.50
▸ RECQL P46063 2/20 0.45
▸ TDP1 Q9NUW8 2/20 0.45
▸ TSHR P16473 1/20 0.42
▸ THRB P10828 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ USP2 O75604 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ ALOX12 P18054 1/20 0.42
▸ BLM P54132 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ MCL1 Q07820 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ EPHX2 P34913 3/20 0.39
▸ RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3859291 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL3868197 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL3863209 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL313504 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL61256 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL9209758 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL3989043 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL9681594 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL8669383 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL3856545 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1390378-B1 PHARMACEUTICALLY ACTIVE URIDINE ESTERS TROMMSDORFF ARZNEIMITTEL (DE) 2009-06-17 — — EP claimed
US-7396826-B2 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2008-07-08 — — US claimed
JP-2004531543-A — — 2004-10-14 — — JP claimed
US-20040121979-A1 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2004-06-24 — — US claimed
EP-1390378-A1 PHARMACEUTICALLY ACTIVE URIDINE ESTERS Trommsdorff GmbH & Co. KG Arzneimittel (DE) 2004-02-25 — — EP claimed
WO-2002088159-A1 PHARMACEUTICALLY ACTIVE URIDINE ESTERS TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2002-11-07 — — WO claimed
US-10588962-B2 Carbohydrate-glycolipid conjugate vaccines MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2020-03-17 — — US disclosed
US-20150238597-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-08-27 — — US disclosed
EP-2827899-B1 POLYSACCHARIDE ANTIGEN-GLYCOLIPID CONJUGATE VACCINES MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V (DE) 2015-08-05 — — EP disclosed
EP-2827899-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-01-28 — — EP disclosed
WO-2013178236-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) 2013-12-05 — — WO disclosed
US-8544658-B2 Functionalized thin film polyamide membranes POLYMERS CRC LIMITED (AU) 2013-10-01 — — US disclosed
WO-2013139803-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2013-09-26 — — WO disclosed
US-6262206-B1 AS POLYMERIZATION INITIATORS FOR POLYMERIZING ETHYLENICALLY UNSATURATED MONOMERS CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-17 — — US disclosed
WO-2001012721-A1 POLYMER BLENDS WITH IMPROVED IMPACT RESISTANCE CIBA SPECIALTY CHEMICALS HOLDINGS INC. (CH) 2001-02-22 — — WO disclosed
EP-1071681-A1 NITROXYL DERIVATIVES WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS INITIATORS FOR RADICAL POLYMERISATION Ciba SC Holding AG (CH) 2001-01-31 — — EP disclosed
EP-0996643-A1 POLYMERIZABLE COMPOSITIONS CONTAINING ALKOXYAMINE COMPOUNDS DERIVED FROM NITROSO- OR NITRONE COMPOUNDS Ciba SC Holding AG (CH) 2000-05-03 — — EP disclosed
WO-1999046261-A1 NITROXYL DERIVATIVES WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS INITIATORS FOR RADICAL POLYMERISATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-09-16 — — WO disclosed
WO-1999003894-A1 POLYMERIZABLE COMPOSITIONS CONTAINING ALKOXYAMINE COMPOUNDS DERIVED FROM NITROSO- OR NITRONE COMPOUNDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-01-28 — — WO disclosed
EP-0891986-A1 Polymerizable compositions containing alkoxyamine compounds derived from nitrogen oxide Ciba SC Holding AG (CH) 1999-01-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150238597-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES STT3B, STT3A, DDOST PTPN7 1933/4885HMGCR 1231/4885RECQL 2785/4885
US-20040121979-A1 Pharmaceutically active uridine esters UMPS, UGDH, FFAR1 PTPN7 4353/4885HMGCR 416/4885RECQL 739/4885
US-10588962-B2 Carbohydrate-glycolipid conjugate vaccines STT3B, STT3A, DDOST PTPN7 1933/4885HMGCR 1231/4885RECQL 2785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.