SCHEMBL1475993

SCHEMBL1475993

[CH2]CCCC#CCC#CCC#CCC#CCCCCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 5/20 0.53
RECQL P46063 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.53
USP2 O75604 1/20 0.53
ALDH1A1 P00352 1/20 0.53
POLB P06746 1/20 0.53
MAPT P10636 1/20 0.53
HPGD P15428 1/20 0.53
ALOX12 P18054 1/20 0.53
BLM P54132 1/20 0.53
KMT2A Q03164 1/20 0.53
MCL1 Q07820 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HMGCR P04035 3/20 0.42
EPHX2 P34913 4/20 0.34
KCNH2 Q12809 1/20 0.32
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3984249 0.93 RECQL (0.55) PTPN7RECQLTDP1KDM4EMEN1
SCHEMBL1551102 0.93 PTPN7 (0.46) PTPN7RECQLTDP1KDM4EMEN1
SCHEMBL10900975 0.91 PTPN7 (0.53) PTPN7RECQLTDP1KDM4EMEN1
SCHEMBL3862473 0.90 PTPN7 (0.50) PTPN7RECQLTDP1KDM4EMEN1
SCHEMBL3215602 0.90 PTPN7 (0.50) PTPN7RECQLTDP1KDM4EMEN1
SCHEMBL7992241 0.90 PTPN7 (0.50) PTPN7RECQLTDP1KDM4EMEN1
SCHEMBL3857559 0.90 PTPN7 (0.50) PTPN7RECQLTDP1KDM4EMEN1
SCHEMBL9344342 0.90 PTPN7 (0.50) PTPN7RECQLTDP1KDM4EMEN1
SCHEMBL17608683 0.90 PTPN7 (0.50) PTPN7RECQLTDP1KDM4EMEN1
SCHEMBL3861223 0.87 PTPN7 (0.46) PTPN7RECQLTDP1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1390378-B1 PHARMACEUTICALLY ACTIVE URIDINE ESTERS TROMMSDORFF ARZNEIMITTEL (DE) 2009-06-17 EP claimed
US-7396826-B2 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2008-07-08 US claimed
US-20040121979-A1 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2004-06-24 US claimed
US-10588962-B2 Carbohydrate-glycolipid conjugate vaccines MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2020-03-17 US disclosed
US-20150238597-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-08-27 US disclosed
EP-2827899-B1 POLYSACCHARIDE ANTIGEN-GLYCOLIPID CONJUGATE VACCINES MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V (DE) 2015-08-05 EP disclosed
US-7915234-B2 Synergistic mixture; antioxidant; cardiovascular disorders; antidiabetic agents TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2011-03-29 US disclosed
US-7560442-B2 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2009-07-14 US disclosed
EP-1390378-B1 PHARMACEUTICALLY ACTIVE URIDINE ESTERS TROMMSDORFF ARZNEIMITTEL (DE) 2009-06-17 EP disclosed
US-7417034-B2 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZENEIMITTEL (DE) 2008-08-26 US disclosed
US-7396826-B2 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2008-07-08 US disclosed
EP-1666092-A2 Drug combination comprising a fatty acid and a uridine compound. Trommsdorff GmbH & Co.KG Arzneimittel (DE) 2006-06-07 EP disclosed
US-20050065110-A1 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO., KG ARZNEIMITTEL 2005-03-24 US disclosed
US-20050043269-A1 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL 2005-02-24 US disclosed
US-20050043394-A1 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL 2005-02-24 US disclosed
US-20040121979-A1 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2004-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050043394-A1 Pharmaceutically active uridine esters UMPS, UGDH, FFAR3 PTPN7 4387/4885RECQL 587/4885TDP1 1664/4885
US-20150238597-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES STT3B, STT3A, DDOST PTPN7 1933/4885RECQL 2785/4885TDP1 4777/4885
US-20040121979-A1 Pharmaceutically active uridine esters UMPS, UGDH, FFAR1 PTPN7 4353/4885RECQL 739/4885TDP1 1177/4885
US-20050043269-A1 Pharmaceutically active uridine esters UMPS, UGDH, FFAR3 PTPN7 4387/4885RECQL 587/4885TDP1 1664/4885
US-20050065110-A1 Pharmaceutically active uridine esters UMPS, UGDH, FFAR3 PTPN7 4387/4885RECQL 587/4885TDP1 1664/4885
US-10588962-B2 Carbohydrate-glycolipid conjugate vaccines STT3B, STT3A, DDOST PTPN7 1933/4885RECQL 2785/4885TDP1 4777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.