SCHEMBL14760201

SCHEMBL14760201

C=C(C)C(=O)[Si](C)(C)C(=O)C(=C)C

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27577063 0.80
SCHEMBL28421243 0.73
SCHEMBL17922844 0.71 ALDH1A1 (0.42) TDP1ALDH1A1HSD17B10
SCHEMBL17922847 0.71 ALDH1A1 (0.42) TDP1ALDH1A1HSD17B10
SCHEMBL31536284 0.67 TDP1 (0.36) TDP1ALDH1A1
SCHEMBL5551390 0.67
SCHEMBL16063 0.65
SCHEMBL8835058 0.65
SCHEMBL8810584 0.65
Methacrylic Acid SCHEMBL491341 0.62 TDP1 (0.53) TDP1ALDH1A1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8716417-B2 Olefin polymerization catalyst and preparation method and use thereof PETROCHINA COMPANY LIMITED (CN) 2014-05-06 US claimed
US-20130072647-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA COMPANY LIMITED (CN) 2013-03-21 US claimed
EP-2567986-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF Petrochina Company Limited (CN) 2013-03-13 EP claimed
US-8716417-B2 Olefin polymerization catalyst and preparation method and use thereof PETROCHINA COMPANY LIMITED (CN) 2014-05-06 US disclosed
US-20130072647-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA COMPANY LIMITED (CN) 2013-03-21 US disclosed
EP-2567986-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF Petrochina Company Limited (CN) 2013-03-13 EP disclosed