SCHEMBL14760241

SCHEMBL14760241

Nc1cc2ccccc2cc1-c1nc2ccccc2[nH]1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 12/20 0.68
RAB9A P51151 12/20 0.68
ALDH1A1 P00352 11/20 0.68
SMN1; SMN2 Q16637 10/20 0.68
HPGD P15428 8/20 0.68
KDM4E B2RXH2 8/20 0.68
HSD17B10 Q99714 6/20 0.68
MAPT P10636 5/20 0.68
NPSR1 Q6W5P4 3/20 0.68
GAA P10253 2/20 0.68
GLA P06280 1/20 0.68
KDR P35968 2/20 0.63
PDGFRB P09619 1/20 0.60
FGFR1 P11362 1/20 0.60
PKM P14618 5/20 0.58
TP53 P04637 4/20 0.58
ABCB11 O95342 1/20 0.58
USP2 O75604 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
CDK1 P06493 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16361085 0.84 ALDH1A1 (0.64) NPC1RAB9AALDH1A1SMN1; SMN2HPGD
SCHEMBL28118423 0.82 ALDH1A1 (0.71) NPC1RAB9AALDH1A1SMN1; SMN2HPGD
SCHEMBL28132179 0.82 ALDH1A1 (0.71) NPC1RAB9AALDH1A1SMN1; SMN2HPGD
SCHEMBL8942811 0.81 KDR (0.65) NPC1RAB9AALDH1A1SMN1; SMN2HPGD
SCHEMBL29424535 0.81 NPC1 (1.00) NPC1RAB9AALDH1A1SMN1; SMN2HPGD
SCHEMBL218892 0.81 NPC1 (1.00) NPC1RAB9AALDH1A1SMN1; SMN2HPGD
SCHEMBL20677815 0.80 NPC1 (0.75) NPC1RAB9AALDH1A1SMN1; SMN2HPGD
SCHEMBL15396523 0.80 ALDH1A1 (0.67) NPC1RAB9AALDH1A1SMN1; SMN2HPGD
SCHEMBL12070828 0.80 NPC1 (0.67) NPC1RAB9AALDH1A1SMN1; SMN2HPGD
SCHEMBL12071677 0.80 ALDH1A1 (0.69) NPC1RAB9AALDH1A1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1960402-B1 NOVEL IMIDAZOQUINAZOLINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2013-03-13 EP disclosed