Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 14/20 | 1.00 |
| ▸ | RAB9A | P51151 | 14/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | HPGD | P15428 | 7/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 1.00 |
| ▸ | CDK1 | P06493 | 1/20 | 0.66 |
| ▸ | CDK2 | P24941 | 1/20 | 0.66 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.66 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | PKM | P14618 | 3/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29424535 | 1.00 | NPC1 (1.00) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28254328 | 0.88 | NPC1 (0.78) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11857261 | 0.86 | NPC1 (0.76) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL227743 | 0.86 | NPC1 (0.78) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL15557394 | 0.85 | SMN1; SMN2 (1.00) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11284874 | 0.83 | ALDH1A1 (0.71) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28118423 | 0.83 | ALDH1A1 (0.71) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28132179 | 0.83 | ALDH1A1 (0.71) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11284879 | 0.83 | GAA (0.73) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL221334 | 0.82 | ALDH1A1 (0.69) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 480 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213338-B | preparation method of pH sensing compound and preparation method of metal coating piece | 深圳市质量安全检验检测研究院 | 2023-12-22 | — | — | CN | claimed |
| CN-117024431-A | Dihydrobenzimidazole quinazoline derivative fluorescent probe and preparation method and application thereof | 河南理工大学 | 2023-11-10 | — | — | CN | claimed |
| CN-113101901-B | Preparation method and application of ferromanganese magnetic graphene oxide lead ion imprinting material | 湖北省烟草科学研究院 | 2023-06-06 | — | — | CN | claimed |
| US-11319328-B2 | 4β-amino substituted podophyllotoxin derivative and preparation method therefor and use thereof | Tang, YaJie | 2022-05-03 | — | — | US | claimed |
| CN-114213338-A | Method for preparing pH sensing compound and method for preparing metal coating piece | 深圳市质量安全检验检测研究院 | 2022-03-22 | — | — | CN | claimed |
| CN-110615802-B | Benzimidazole quinazoline derivative and preparation method and application thereof | 江苏师范大学 | 2022-03-15 | — | — | CN | claimed |
| CN-108285455-B | 4 beta-amino substituted podophyllotoxin derivative and preparation method and application thereof | 汤亚杰 | 2022-02-08 | — | — | CN | claimed |
| CN-113101901-A | Preparation method and application of ferromanganese magnetic graphene oxide lead ion imprinted material | 湖北省烟草科学研究院 | 2021-07-13 | — | — | CN | claimed |
| US-20210140052-A1 | ELECTROLESS COPPER PLATING AND COUNTERACTING PASSIVATION | ROHM AND HAAS ELECTRONIC MATERIALS LLC | 2021-05-13 | — | — | US | claimed |
| EP-3819397-A1 | ELECTROLESS COPPER PLATING AND COUNTERACTING PASSIVATION | Rohm and Haas Electronic Materials LLC (US) | 2021-05-12 | — | — | EP | claimed |
| US-8053762-B2 | Imidazoquinazoline derivative, process for preparing the same, and organic electronic device using the same | LG CHEM, LTD. (KR) | 2011-11-08 | — | — | US | claimed |
| US-20110081428-A1 | Use of thioflavin-like compounds to increase life span and/or health span | THE BUCK INSTITUTE FOR AGE RESEARCH | 2011-04-07 | — | — | US | claimed |
| EP-2274460-A1 | ADHESION PROMOTION OF METAL TO LAMINATE WITH A MULTI-FUNCTIONAL COMPOUND HAFTFORDERUNG VON METALL ZU LAMINATEN MIT EINER MULTIFUNKTIONELLEN | Enthone, Inc. (US) | 2011-01-19 | — | — | EP | claimed |
| WO-2007069847-A9 | NOVEL IMIDAZOQUINAZOLINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM. LTD. (KR) | 2010-12-16 | — | — | WO | claimed |
| WO-2009117734-A1 | ADHESION PROMOTION OF METAL TO LAMINATE WITH A MULTI-FUNCTIONAL COMPOUND HAFTFORDERUNG VON METALL ZU LAMINATEN MIT EINER MULTIFUNKTIONELLEN | ENTHONE INC. (US) | 2009-09-24 | — | — | WO | claimed |
| CN-101291935-A | Novel imidazoquinazoline derivative, method for preparing same, and organic electronic device using same | LG CHEMICAL LTD (KR) | 2008-10-22 | — | — | CN | claimed |
| EP-1960402-A1 | NOVEL IMIDAZOQUINAZOLINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG Chem, Ltd. (KR) | 2008-08-27 | — | — | EP | claimed |
| WO-2007069847-A1 | NOVEL IMIDAZOQUINAZOLINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM. LTD. (KR) | 2007-06-21 | — | — | WO | claimed |
| US-20070131929-A1 | Novel imidazoquinazoline derivative, process for preparing the same, and organic electronic device using the same | LG CHEM. LTD. (KR) | 2007-06-14 | — | — | US | claimed |
| US-4662905-A | REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE | Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) | 1987-05-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110081428-A1 | Use of thioflavin-like compounds to increase life span and/or health span | HTT, POT1, TST | NPC1 1250/4885RAB9A 3792/4885ALDH1A1 741/4885 |
| US-11319328-B2 | 4β-amino substituted podophyllotoxin derivative and preparation method therefor and use thereof | WEE1, WEE2, CYP51A1 | NPC1 4117/4885RAB9A 1531/4885ALDH1A1 1581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.