Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 6/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2841049 | 1.00 | LPAR1 (0.48) | LPAR1LPAR3LPAR2LTA4HDNM1 | |
| SCHEMBL2838688 | 1.00 | LPAR1 (0.48) | LPAR1LPAR3LPAR2LTA4HDNM1 | |
| SCHEMBL2838586 | 1.00 | LPAR1 (0.48) | LPAR1LPAR3LPAR2LTA4HDNM1 | |
| SCHEMBL3488089 | 0.92 | ALDH1A1 (0.47) | LPAR1LPAR3LPAR2 | |
| SCHEMBL14760008 | 0.92 | ALDH1A1 (0.47) | LPAR1LPAR3LPAR2 | |
| SCHEMBL14760007 | 0.92 | ALDH1A1 (0.47) | LPAR1LPAR3LPAR2 | |
| SCHEMBL2835879 | 0.92 | ALDH1A1 (0.47) | LPAR1LPAR3LPAR2 | |
| SCHEMBL16371200 | 0.88 | ALDH1A1 (0.53) | LPAR1LPAR3 | |
| SCHEMBL2841053 | 0.88 | ALDH1A1 (0.53) | LPAR1LPAR3 | |
| SCHEMBL2879443 | 0.88 | ALDH1A1 (0.53) | LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130129811-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130129811-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130129811-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2013-05-23 | — | — | US | disclosed |
| EP-2567952-A1 | CATIONIC LIPID | Kyowa Hakko Kirin Co., Ltd. (JP) | 2013-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129811-A1 | CATIONIC LIPID | ACOX3, LPCAT1, ACOX1 | LPAR1 16/4885LPAR3 5/4885LPAR2 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.