Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.44 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.44 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.44 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14716612 | 0.87 | ALDH1A1 (0.46) | EEDRBBP4SUZ12AEBP2ALDH1A1 | |
| SCHEMBL14716843 | 0.82 | EED (0.60) | EEDRBBP4SUZ12AEBP2PDE3B | |
| SCHEMBL15797726 | 0.80 | CYP1A2 (0.44) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL15174113 | 0.78 | EED (0.46) | EEDRBBP4SUZ12AEBP2KDM4E | |
| SCHEMBL14734270 | 0.73 | EZH2 (0.41) | EEDRBBP4SUZ12AEBP2PDE3B | |
| SCHEMBL2594511 | 0.70 | PARP1 (0.50) | ALDH1A1KDM4EADORA1DAOPARP1 | |
| SCHEMBL9887612 | 0.69 | EED (0.53) | EEDRBBP4SUZ12AEBP2PDE3B | |
| SCHEMBL9277469 | 0.69 | LMNA (0.45) | ALDH1A1KDM4EHSD17B10ADORA1PARP1 | |
| Hydrochloric Acid SCHEMBL2594087 | 0.69 | PARP1 (0.49) | ALDH1A1KDM4EADORA1DAOPARP1 | |
| SCHEMBL9286770 | 0.68 | PARP1 (0.51) | ALDH1A1KDM4EHPGDADORA1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566328-A1 | INDAZOLES | GlaxoSmithKline LLC (US) | 2013-03-13 | — | — | EP | disclosed |