Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.72 |
| ▸ | DRD4 | P21917 | 7/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.72 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.72 |
| ▸ | HTR7 | P34969 | 3/20 | 0.72 |
| ▸ | HTR2B | P41595 | 3/20 | 0.72 |
| ▸ | HTR2A | P28223 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | HTR1B | P28222 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14762076 | 0.94 | HTR1A (0.63) | HTR1ADRD4ADRA1AADRA1BHTR7 | |
| SCHEMBL14761341 | 0.86 | HTR1A (0.53) | HTR1ADRD4ADRA1AADRA1BHTR7 | |
| SCHEMBL8010894 | 0.84 | HTR1A (1.00) | HTR1ADRD4ADRA1AADRA1BHTR7 | |
| SCHEMBL14761356 | 0.82 | HTR1A (0.46) | HTR1ADRD4ADRA1AADRA1BHTR7 | |
| SCHEMBL8013725 | 0.81 | HTR1A (1.00) | HTR1ADRD4ADRA1AADRA1BHTR7 | |
| SCHEMBL9196408 | 0.81 | HTR1A (0.82) | HTR1ADRD4ADRA1AADRA1BHTR7 | |
| Hydrochloric Acid SCHEMBL29989604 | 0.80 | HTR1A (0.98) | HTR1ADRD4ADRA1AADRA1BHTR7 | |
| SCHEMBL7956992 | 0.80 | HTR1A (0.78) | HTR1ADRD4ADRA1AADRA1BHTR7 | |
| SCHEMBL7956811 | 0.80 | HTR1A (0.78) | HTR1ADRD4ADRA1AADRA1BHTR7 | |
| SCHEMBL7956950 | 0.79 | HTR1A (0.78) | HTR1ADRD4ADRA1AADRA1BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130064770-A1 | RADIOLABELED COMPOUNDS AND METHODS THEREOF | GE HEALTHCARE LIMITED (GB) | 2013-03-14 | — | — | US | disclosed |
| US-20130064770-A1 | RADIOLABELED COMPOUNDS AND METHODS THEREOF | GE HEALTHCARE LIMITED (GB) | 2013-03-14 | — | — | US | disclosed |
| US-20130064770-A1 | RADIOLABELED COMPOUNDS AND METHODS THEREOF | GE HEALTHCARE LIMITED (GB) | 2013-03-14 | — | — | US | disclosed |
| WO-2011150183-A1 | RADIOLABELED COMPOUNDS AND METHODS THEREOF | GE HEALTHCARE LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130064770-A1 | RADIOLABELED COMPOUNDS AND METHODS THEREOF | HTR5A, HTR3B, HTR1A | HTR1A 3/4885DRD4 109/4885ADRA1A 207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.