Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122146 | 0.86 | POLB (0.43) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3548773 | 0.85 | MMP2 (0.41) | ALDH1A1MEN1KMT2ACYP2C19KDM4E | |
| SCHEMBL3548775 | 0.85 | MMP2 (0.41) | ALDH1A1MEN1KMT2ACYP2C19KDM4E | |
| SCHEMBL31696759 | 0.85 | MMP2 (0.41) | ALDH1A1MEN1KMT2ACYP2C19KDM4E | |
| SCHEMBL5200976 | 0.85 | MMP2 (0.41) | ALDH1A1MEN1KMT2ACYP2C19KDM4E | |
| SCHEMBL26062663 | 0.85 | MMP2 (0.41) | ALDH1A1MEN1KMT2ACYP2C19KDM4E | |
| SCHEMBL29276034 | 0.85 | MMP2 (0.41) | ALDH1A1MEN1KMT2ACYP2C19KDM4E | |
| SCHEMBL25366582 | 0.81 | ATM (0.41) | MEN1KMT2ARIPK1CHRM2CHRM4 | |
| SCHEMBL5204041 | 0.81 | ATM (0.41) | MEN1KMT2ARIPK1CHRM2CHRM4 | |
| SCHEMBL14762600 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CACNA1ACACNA2D1CACNB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512074-B2 | Radiolabeled inhibitors of the amino acid transporters ASCT1 and ASCT2 | THE UNIVERSITY OF MONTANA (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150056138-A1 | Radiolabeled Inhibitors of the Amino Acid Transporters ASCT1 and ASCT2 | THE UNIVERSITY OF MONTANA | 2015-02-26 | — | — | US | disclosed |
| US-8895607-B2 | Inhibitors of the amino acid transporters ASCT1 and ASCT2 | THE UNIVERSITY OF MONTANA (US) | 2014-11-25 | — | — | US | disclosed |
| US-20130065935-A1 | Novel Inhibitors of the Amino Acid Transporters ASCT1 and ASCT2 | THE UNIVERSITY OF MONTANA | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065935-A1 | Novel Inhibitors of the Amino Acid Transporters ASCT1 and ASCT2 | SLC1A2, SLC1A1, SLC1A3 | ALDH1A1 1325/4885CACNA1A 1757/4885CACNA2D1 2146/4885 |
| US-20150056138-A1 | Radiolabeled Inhibitors of the Amino Acid Transporters ASCT1 and ASCT2 | SLC1A2, SLC1A1, SLC1A3 | ALDH1A1 1172/4885CACNA1A 1570/4885CACNA2D1 2023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.