Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 3/20 | 0.43 |
| ▸ | CDC25B | P30305 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764954 | 0.98 | MAPT (0.50) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL24784356 | 0.98 | MAPT (0.50) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL572112 | 0.84 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL5820368 | 0.83 | MAPT (0.58) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL572109 | 0.83 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL571040 | 0.83 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL571017 | 0.83 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL571286 | 0.83 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL571607 | 0.83 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL572045 | 0.83 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036766-A1 | SMALL MOLECULE NAPHTHOQUINONE- AND PHTHALIMIDE-BASED LIPOCATIONS AS ANTI-PARASITIC AGENTS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-03-14 | — | — | WO | disclosed |