SCHEMBL1476496

SCHEMBL1476496

Cc1c(N)ccc2cc(C(=O)O)ccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.49
KDM4E B2RXH2 5/20 0.46
CDC25B P30305 1/20 0.46
LMNA P02545 1/20 0.44
ALDH1A1 P00352 5/20 0.42
HPGD P15428 4/20 0.42
THRB P10828 3/20 0.42
GRM1 Q13255 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 4/20 0.42
GAA P10253 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
GFER P55789 2/20 0.42
NPC1 O15118 2/20 0.42
GLA P06280 1/20 0.42
HSD17B10 Q99714 1/20 0.42
RCE1 Q9Y256 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6007565 0.86 PTPN1 (0.51) PTPN1KDM4ECDC25BLMNAALDH1A1
SCHEMBL8529516 0.83 ALDH1A1 (0.58) PTPN1KDM4ELMNAALDH1A1HPGD
SCHEMBL18936286 0.82 PTPN1 (0.51) PTPN1KDM4EALDH1A1HPGDTHRB
SCHEMBL30218705 0.82 PTPN1 (0.51) PTPN1KDM4EALDH1A1HPGDTHRB
SCHEMBL342574 0.81 PTPN1 (0.50) PTPN1KDM4ECDC25BLMNAALDH1A1
SCHEMBL2748359 0.81 ESR1 (0.53) PTPN1KDM4EALDH1A1HPGDTHRB
SCHEMBL28205088 0.81 PTPN1 (0.50) PTPN1KDM4ECDC25BLMNAALDH1A1
SCHEMBL2749203 0.81 PTPN1 (0.59) PTPN1KDM4EALDH1A1HPGDTHRB
SCHEMBL1477373 0.79 PTPN1 (0.49) PTPN1KDM4ECDC25BLMNAALDH1A1
SCHEMBL7088722 0.79 PTPN1 (0.64) PTPN1KDM4EALDH1A1HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1845967-A Delamination-resistant barrier polyamide composition for three-layer PET beverage bottle HONEYWELL INT INC (US) 2006-10-11 CN claimed
US-8496616-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-07-30 US disclosed
EP-1991286-B1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENT LTD (BB) 2012-12-26 EP disclosed
US-20120220932-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-08-30 US disclosed
US-8187492-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-05-29 US disclosed
US-20110092999-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-04-21 US disclosed
US-7914485-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-03-29 US disclosed
US-7857785-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-12-28 US disclosed
US-20100145269-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-06-10 US disclosed
US-7662129-B2 Block copolymer containing A block is a liquid crystal polymer block formed from repeating units comprising mesogenic groups and has a polymer backbone comprising no aliphatic unsaturation; and the B block is a non-liquid crystal polymer block; catheters BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-02-16 US disclosed
US-20070191813-A1 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. 2007-08-16 US disclosed
US-20070191814-A1 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2007-08-16 US disclosed
US-6143823-A POLYESTER, POLYAMIDE, POLYETHER, POLYCARBONATE, POLYLACTAM, AND/OR POLYLACTONE CONDENSATES BLENDED WITH OLEFIN POLYMER; IMPACT AND TENSILE STRENGTH; CHEMICAL AND HEAT RESISTANCE BAYER AG (DE) 2000-11-07 US disclosed
EP-0595082-B1 Thermoplastically processable thermotropic moulding composition BAYER AG (DE) 1999-05-06 EP disclosed
EP-0432561-B1 Graft cocondensate made of a polyarylenesulfide backbone and side chains with liquid crystal properties BAYER AG (DE) 1995-06-07 EP disclosed
EP-0595082-A2 Thermoplastically processable thermotropic moulding composition BAYER AG (DE) 1994-05-04 EP disclosed
EP-0330037-B1 Thermoplastic block copolymers comprising blocks of carboxyl groups containing polypropylene and blocks of completely aromatic polyesters, polyestercarbonates or polyesteramides. BAYER AG (DE) 1993-04-21 EP disclosed
US-5162434-A Molded articles, filaments, fibers, films BAYER AKTIENGESELLSCHAFT (DE) 1992-11-10 US disclosed
US-5030703-A Polyesters, polycarbonateesters, polylactones BAYER AKTIENGESELLSCHAFT (DE) 1991-07-09 US disclosed
EP-0432561-A2 Graft cocondensate made of a polyarylenesulfide backbone and side chains with liquid crystal properties BAYER AG (DE) 1991-06-19 EP disclosed