SCHEMBL6007565

SCHEMBL6007565

Nc1ccc2cc(C(=O)O)ccc2c1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.51
CDC25B P30305 1/20 0.49
LMNA P02545 1/20 0.46
KDM4E B2RXH2 6/20 0.44
GRIN2D O15399 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2C Q14957 1/20 0.44
RARA P10276 4/20 0.43
RARB P10826 4/20 0.43
RARG P13631 4/20 0.43
CYP26A1 O43174 1/20 0.43
CYP26B1 Q9NR63 1/20 0.43
ALDH1A1 P00352 4/20 0.41
HPGD P15428 4/20 0.41
HSD17B10 Q99714 4/20 0.41
ENPP2 Q13822 1/20 0.41
MAPT P10636 4/20 0.40
GAA P10253 4/20 0.40
THRB P10828 2/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6051366 0.87 CDC25B (0.50) PTPN1CDC25BLMNAKDM4EGRIN2D
SCHEMBL1476496 0.86 PTPN1 (0.49) PTPN1CDC25BLMNAKDM4EGRIN2D
SCHEMBL5800894 0.84 PTPN1 (0.59) PTPN1CDC25BKDM4EGRIN2DGRIN2A
SCHEMBL29364605 0.84 PTPN1 (0.59) PTPN1CDC25BKDM4EGRIN2DGRIN2A
SCHEMBL28205088 0.84 PTPN1 (0.50) PTPN1CDC25BLMNAKDM4EGRIN2D
SCHEMBL342574 0.84 PTPN1 (0.50) PTPN1CDC25BLMNAKDM4EGRIN2D
SCHEMBL1477373 0.82 PTPN1 (0.49) PTPN1CDC25BLMNAKDM4EGRIN2D
SCHEMBL8529516 0.82 ALDH1A1 (0.58) PTPN1LMNAKDM4EGRIN2DGRIN2A
SCHEMBL7088722 0.82 PTPN1 (0.64) PTPN1KDM4EGRIN2DGRIN2AGRIN2C
SCHEMBL9119115 0.79 PTPN1 (0.53) PTPN1CDC25BKDM4EGRIN2DGRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0967674-B1 Solid polymer electrolytes HONDA MOTOR CO LTD (JP) 2006-03-22 EP disclosed
US-6124060-A A POLY-2,5-BENZIMIDAZOLE DOPED WITH AN ACID IN WHICH A HYDROGEN ATOM OF AN INORGANIC ACID IS REPLACED WITH A PHENYL GROUP; MADE BY A WRINKLE-RESISTANT SOLUTION BLEND METHOD; LOW WATER ABSORPTION; NO DOPANT LEAKAGE WHEN PRESSED; FUEL CELLS HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2000-09-26 US disclosed
EP-0967674-A1 Solid polymer electrolytes HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 1999-12-29 EP disclosed
WO-1998037940-A1 METHOD OF REMOVING IMPURITIES FROM POLYMERS UTILIZING FACILITATED ION EXCHANGE HOECHST CELANESE CORPORATION (US) 1998-09-03 WO disclosed
US-5599639-A Acid-modified polybenzimidazole fuel cell elements HOECHST CELANESE CORPORATION (US) 1997-02-04 US disclosed
US-5264542-A Molding polybenzimidazole by immersion in a bath, sintering, heating and drying HOECHST CELANESE CORP. (US) 1993-11-23 US disclosed
WO-1991007455-A1 SULFOALKYLATION OF HYDROXYETHYLATED POLYBENZIMIDAZOLE POLYMERS HOECHST CELANESE CORPORATION (US) 1991-05-30 WO disclosed
US-4997892-A Sulfalkylation of hydroxyethylated polybenzimidazole polymers HOECHST CELANESE CORP. (US) 1991-03-05 US disclosed
EP-0354040-A2 Membranes prepared from blends of polybenzimidazole with polyarylates HOECHST CELANESE CORPORATION (US) 1990-02-07 EP disclosed
US-4868249-A Cyanoethylation of hydroxyethylated polybenzimidazole polymers HOECHST CELANESE CORP. (US) 1989-09-19 US disclosed
US-4452972-A Production of high molecular weight polybenzimidazole with aryl phosphonic acid or aryl phosphinic acid catalyst CELANESE CORPORATION (US) 1984-06-05 US disclosed
US-4452967-A MELT POLYMERIZATION OF AROMATIC CARBOXY DIAMINE CELANESE CORPORATION (US) 1984-06-05 US disclosed
US-4448954-A Single stage production of improved high molecular weight polybenzimidazole with organosilicon halide catalyst. CELANESE CORPORATION (US) 1984-05-15 US disclosed
US-4448955-A Production of improved high molecular weight polybenzimidazole with tin containing catalyst CELANESE CORPORATION (US) 1984-05-15 US disclosed
EP-0103978-A1 Single stage production of improved high molecular weight polybenzimidazole CELANESE CORPORATION (US) 1984-03-28 EP disclosed
EP-0102171-A1 Production of improved high molecular weight polybenzimidazoles CELANESE CORPORATION (US) 1984-03-07 EP disclosed
US-4431796-A HEATING A MELT OF AROMATIC TETRAAMINE AND AROMATIC DICARBOXYLIC AC CELANESE CORPORATION (US) 1984-02-14 US disclosed
EP-0095348-A2 High molecular weight polybenzimidazoles CELANESE CORPORATION (US) 1983-11-30 EP disclosed
US-4414383-A High molecular weight polybenzimidazole preparation with phosphorus containing polymerization catalyst CELANESE CORPORATION (US) 1983-11-08 US disclosed
US-4312976-A Single-stage melt polymerization process for the production of high molecular weight polybenzimidazole CELANESE CORPORATION (US) 1982-01-26 US disclosed