Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22069493 | 1.00 | TAS1R3 (0.47) | TAS1R3TAS1R1LMNASTAT3RAB9A | |
| SCHEMBL19946462 | 1.00 | TAS1R3 (0.47) | TAS1R3TAS1R1LMNASTAT3RAB9A | |
| SCHEMBL2682576 | 0.87 | TAS1R3 (0.48) | TAS1R3TAS1R1LMNARAB9ANPC1 | |
| SCHEMBL19946452 | 0.87 | TAS1R3 (0.48) | TAS1R3TAS1R1LMNARAB9ANPC1 | |
| SCHEMBL22380835 | 0.81 | TAS1R3 (0.44) | TAS1R3TAS1R1LMNARAB9ATSHR | |
| SCHEMBL668773 | 0.81 | TAS1R3 (0.44) | TAS1R3TAS1R1LMNARAB9ATSHR | |
| SCHEMBL668914 | 0.79 | LMNA (0.46) | TAS1R3TAS1R1LMNASTAT3RAB9A | |
| SCHEMBL3774894 | 0.79 | TAS1R3 (0.42) | TAS1R3TAS1R1TSHRPRSS1CTSG | |
| SCHEMBL3766136 | 0.78 | STAT3 (0.52) | LMNASTAT3RAB9ANPC1CTSD | |
| SCHEMBL669098 | 0.77 | ABCB1 (0.46) | TAS1R3TAS1R1LMNASTAT3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167458-B1 | CHIRAL DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | INTREXON CORP (US) | 2018-03-14 | — | — | EP | claimed |
| CN-110139933-A | Frataxin expression construct | 英特瑞克斯顿股份有限公司 | 2019-08-16 | — | — | CN | disclosed |
| EP-2751072-A1 | CRYSTALLINE DIACYLHYDRAZINE AND THE USE THEREOF | Intrexon Corporation (US) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013036758-A8 | CRYSTALLINE DIACYLHYDRAZINE AND THE USE THEREOF | INTREXON CORPORATION (US) | 2013-10-03 | — | — | WO | disclosed |
| WO-2013036758-A1 | CRYSTALLINE DIACYLHYDRAZINE AND THE USE THEREOF | INTREXON CORPORATION (US) | 2013-03-14 | — | — | WO | disclosed |