Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 20/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.56 |
| ▸ | PDE6D | O43924 | 4/20 | 0.50 |
| ▸ | PDE6A | P16499 | 4/20 | 0.50 |
| ▸ | PDE6G | P18545 | 4/20 | 0.50 |
| ▸ | PDE6B | P35913 | 4/20 | 0.50 |
| ▸ | PDE6C | P51160 | 4/20 | 0.50 |
| ▸ | PDE6H | Q13956 | 4/20 | 0.50 |
| ▸ | PDE4A | P27815 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765186 | 0.89 | PDE2A (0.72) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL14771537 | 0.86 | PDE2A (0.56) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL14764861 | 0.83 | PDE2A (0.78) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL14771474 | 0.76 | PDE2A (0.72) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL14765096 | 0.72 | PDE2A (1.00) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL3324690 | 0.71 | PDE2A (0.67) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL14765184 | 0.71 | PDE2A (0.66) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL14765187 | 0.71 | PDE2A (0.67) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL14765020 | 0.70 | PDE2A (0.65) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL14765076 | 0.70 | PDE2A (0.72) | PDE2APDE10APDE6DPDE6APDE6G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034758-A1 | SUBSTITUTED TRIAZOLOPYRAZINES AND USES THEREOF | H. LUNDBECK A/S (DK) | 2013-03-14 | — | — | WO | claimed |
| WO-2013034758-A1 | SUBSTITUTED TRIAZOLOPYRAZINES AND USES THEREOF | H. LUNDBECK A/S (DK) | 2013-03-14 | — | — | WO | disclosed |