Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645403 | 0.87 | RAB9A (0.45) | HPGDALDH1A1PTGS1PTGS2LMNA | |
| SCHEMBL14645236 | 0.86 | RAB9A (0.41) | HPGDALDH1A1PTGS1PTGS2LMNA | |
| SCHEMBL14645324 | 0.76 | NPSR1 (0.38) | HPGDALDH1A1CYP2C9LMNAKDM4E | |
| SCHEMBL14646189 | 0.76 | ALDH1A1 (0.55) | HPGDALDH1A1PTGS1PTGS2CYP2C9 | |
| SCHEMBL14645498 | 0.76 | KMT2A (0.49) | HPGDALDH1A1PTGS1PTGS2CYP2C9 | |
| SCHEMBL14645336 | 0.74 | NPSR1 (0.43) | HPGDALDH1A1CYP2C9LMNAKDM4E | |
| SCHEMBL9976580 | 0.71 | KDM4E (0.47) | HPGDALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL15695284 | 0.70 | MEN1 (0.41) | HPGDALDH1A1CYP2C9LMNARXFP1 | |
| SCHEMBL14646181 | 0.68 | KMT2A (0.41) | HPGDALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL14645455 | 0.67 | KMT2A (0.34) | HPGDALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036196-A1 | NOVEL THIOPHENE COMPOUNDS AND METHOD FOR IN VIVO IMAGING | BIOCHROMIX AB (SE) | 2013-03-14 | — | — | WO | disclosed |