Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19479759 | 0.89 | ABCB1 (0.36) | ABCB1MAOAACHEMAPTMEN1 | |
| SCHEMBL17728762 | 0.87 | ABCB1 (0.37) | ABCB1MAOAACHEMAPTMEN1 | |
| SCHEMBL19389074 | 0.86 | ABCB1 (0.39) | ABCB1MAOAACHEMAPTMEN1 | |
| SCHEMBL12879880 | 0.86 | ABCB1 (0.39) | ABCB1MAOAACHEMAPTMEN1 | |
| SCHEMBL28634475 | 0.85 | ABCB1 (0.38) | ABCB1MAOAACHEMAPTMEN1 | |
| SCHEMBL28634476 | 0.85 | ABCB1 (0.38) | ABCB1MAOAACHEMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL28631038 | 0.85 | ABCB1 (0.38) | ABCB1MAOAACHEMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL28631036 | 0.85 | ABCB1 (0.38) | ABCB1MAOAACHEMAPTMEN1 | |
| SCHEMBL12879803 | 0.84 | ABCB1 (0.40) | ABCB1MAOAACHEMAPTMEN1 | |
| SCHEMBL15134790 | 0.84 | ABCB1 (0.40) | ABCB1MAOAACHEMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394922-B2 | Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof | MEDAREX, INC. (US) | 2013-03-12 | — | — | US | disclosed |