Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634475 | 1.00 | ABCB1 (0.38) | ABCB1CA2MAOAACHEPTPRB | |
| SCHEMBL24140397 | 0.89 | ABCB1 (0.48) | ABCB1CA2PTPRBMEN1NPC1 | |
| SCHEMBL14765446 | 0.85 | ABCB1 (0.38) | ABCB1CA2MAOAACHEPTPRB | |
| SCHEMBL19479759 | 0.82 | ABCB1 (0.36) | ABCB1CA2MAOAACHEMEN1 | |
| SCHEMBL28064131 | 0.82 | ABCB1 (0.52) | ABCB1CA2PTPRB | |
| SCHEMBL28064130 | 0.82 | ABCB1 (0.52) | ABCB1CA2PTPRB | |
| SCHEMBL17728762 | 0.80 | ABCB1 (0.37) | ABCB1CA2MAOAACHEMEN1 | |
| SCHEMBL22154581 | 0.80 | ABCB1 (0.37) | ABCB1CA2PTPRB | |
| SCHEMBL28646527 | 0.80 | ABCB1 (0.37) | ABCB1CA2PTPRB | |
| SCHEMBL19389074 | 0.79 | ABCB1 (0.39) | ABCB1CA2MAOAACHEPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454097-A | Tubulysins and protein-tubulysin conjugates | 里珍纳龙药品有限公司 | 2021-09-28 | — | — | CN | disclosed |