Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13484540 | 0.86 | PPARD (0.78) | PPARDPPARA | |
| SCHEMBL14765473 | 0.82 | PPARD (0.56) | PPARDPPARAL3MBTL1POLBMAPT | |
| SCHEMBL14765472 | 0.82 | PPARD (0.56) | PPARDPPARAL3MBTL1POLBMAPT | |
| SCHEMBL14765479 | 0.79 | PPARD (0.72) | PPARDPPARAKDM4EL3MBTL1NPSR1 | |
| SCHEMBL14765474 | 0.76 | PPARD (0.62) | PPARDPPARAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL3199595 | 0.75 | PPARD (0.61) | PPARDPPARAALDH1A1MAPT | |
| SCHEMBL14124587 | 0.75 | PPARD (0.60) | PPARDPPARAALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL3210801 | 0.75 | PPARD (0.74) | PPARDPPARA | |
| SCHEMBL14765468 | 0.74 | PPARD (0.57) | PPARDPPARAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL13484537 | 0.73 | PPARD (0.74) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394841-B2 | Compounds and methods for modulating G protein-coupled receptors | IRM LLC (BM) | 2013-03-12 | — | — | US | disclosed |