Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 6/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | ATP4A | P20648 | 2/20 | 0.44 |
| ▸ | ATP4B | P51164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765473 | 0.93 | PPARD (0.56) | PPARDPPARAHTR3AL3MBTL1POLB | |
| SCHEMBL13484537 | 0.89 | PPARD (0.74) | PPARDPPARA | |
| SCHEMBL14765479 | 0.87 | PPARD (0.72) | PPARDPPARAHTR3AL3MBTL1POLB | |
| SCHEMBL14765467 | 0.82 | PPARD (0.56) | PPARDPPARAL3MBTL1POLBNPC1 | |
| SCHEMBL14765474 | 0.82 | PPARD (0.62) | PPARDPPARACYP19A1L3MBTL1POLB | |
| SCHEMBL14765468 | 0.80 | PPARD (0.57) | PPARDPPARAL3MBTL1POLBMEN1 | |
| SCHEMBL28701419 | 0.79 | PPARD (0.47) | PPARDPPARAHTR3ACYP19A1MAPT | |
| SCHEMBL13484533 | 0.77 | PPARD (0.69) | PPARDPPARA | |
| SCHEMBL3194256 | 0.77 | PPARD (0.61) | PPARDPPARA | |
| SCHEMBL3199595 | 0.77 | PPARD (0.61) | PPARDPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394841-B2 | Compounds and methods for modulating G protein-coupled receptors | IRM LLC (BM) | 2013-03-12 | — | — | US | disclosed |