Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.62 |
| ▸ | PPARA | Q07869 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ATP4A | P20648 | 1/20 | 0.46 |
| ▸ | ATP4B | P51164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765479 | 0.90 | PPARD (0.72) | PPARDPPARAL3MBTL1POLBMAPT | |
| SCHEMBL14765468 | 0.89 | PPARD (0.57) | PPARDPPARAL3MBTL1POLBMAPT | |
| SCHEMBL13484538 | 0.88 | PPARD (0.82) | PPARDPPARA | |
| SCHEMBL14765473 | 0.82 | PPARD (0.56) | PPARDPPARAL3MBTL1POLBMAPT | |
| SCHEMBL14765472 | 0.82 | PPARD (0.56) | PPARDPPARAL3MBTL1POLBCYP19A1 | |
| SCHEMBL13484529 | 0.78 | PPARD (0.67) | PPARDPPARAL3MBTL1POLB | |
| SCHEMBL3194317 | 0.77 | PPARD (0.82) | PPARDPPARA | |
| SCHEMBL28679894 | 0.77 | PPARD (0.52) | PPARDPPARAL3MBTL1POLBCYP19A1 | |
| SCHEMBL23657731 | 0.77 | L3MBTL1 (0.72) | PPARDPPARAL3MBTL1POLBCYP19A1 | |
| SCHEMBL10272063 | 0.77 | CYP19A1 (0.59) | CYP19A1DRD4DRD2MAPTSREBF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394841-B2 | Compounds and methods for modulating G protein-coupled receptors | IRM LLC (BM) | 2013-03-12 | — | — | US | disclosed |