Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765485 | 0.90 | BCHE (0.49) | MAPTL3MBTL1ALDH1A1NPSR1CYP19A1 | |
| SCHEMBL14765475 | 0.90 | L3MBTL1 (0.55) | MAPTL3MBTL1ALDH1A1NPSR1CYP19A1 | |
| SCHEMBL14765480 | 0.89 | L3MBTL1 (0.53) | MAPTL3MBTL1ALDH1A1NPSR1CYP19A1 | |
| SCHEMBL14765486 | 0.86 | L3MBTL1 (0.45) | MAPTL3MBTL1ALDH1A1NPSR1CYP19A1 | |
| SCHEMBL14765488 | 0.84 | L3MBTL1 (0.45) | MAPTL3MBTL1ALDH1A1NPSR1CYP19A1 | |
| SCHEMBL13484565 | 0.83 | NPC1 (0.60) | MAPTL3MBTL1ALDH1A1NPSR1CYP19A1 | |
| SCHEMBL13484545 | 0.83 | PPARD (0.53) | MAPTL3MBTL1ALDH1A1NPSR1CYP19A1 | |
| SCHEMBL14765476 | 0.81 | CYP1A2 (0.50) | MAPTL3MBTL1ALDH1A1NPSR1CYP19A1 | |
| SCHEMBL13484542 | 0.81 | PPARD (0.50) | MAPTL3MBTL1ALDH1A1NPSR1NPC1 | |
| SCHEMBL13484547 | 0.81 | PPARG (0.48) | MAPTL3MBTL1ALDH1A1NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394841-B2 | Compounds and methods for modulating G protein-coupled receptors | IRM LLC (BM) | 2013-03-12 | — | — | US | disclosed |