Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ATP4A | P20648 | 2/20 | 0.39 |
| ▸ | ATP4B | P51164 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13484548 | 0.87 | PPARA (0.46) | L3MBTL1ALDH1A1NPSR1BCHEMAPT | |
| SCHEMBL14765481 | 0.86 | MAPT (0.47) | L3MBTL1ALDH1A1NPSR1CYP19A1MAPT | |
| SCHEMBL14765485 | 0.86 | BCHE (0.49) | L3MBTL1ALDH1A1NPSR1CYP19A1BCHE | |
| SCHEMBL14765475 | 0.86 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1NPSR1CYP19A1MAPT | |
| SCHEMBL14765480 | 0.86 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1NPSR1CYP19A1MAPT | |
| SCHEMBL14765488 | 0.81 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1NPSR1CYP19A1BCHE | |
| SCHEMBL13484554 | 0.81 | FFAR2 (0.46) | L3MBTL1ALDH1A1NPSR1BCHEMAPT | |
| SCHEMBL13484557 | 0.81 | CTSA (0.46) | L3MBTL1ALDH1A1NPSR1BCHEMAPT | |
| SCHEMBL13484565 | 0.80 | NPC1 (0.60) | L3MBTL1ALDH1A1NPSR1CYP19A1MAPT | |
| SCHEMBL13484545 | 0.80 | PPARD (0.53) | L3MBTL1ALDH1A1NPSR1CYP19A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394841-B2 | Compounds and methods for modulating G protein-coupled receptors | IRM LLC (BM) | 2013-03-12 | — | — | US | disclosed |