Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.37 |
| ▸ | PRKCG | P05129 | 2/20 | 0.37 |
| ▸ | PRKCB | P05771 | 2/20 | 0.37 |
| ▸ | PRKCA | P17252 | 2/20 | 0.37 |
| ▸ | PRKCH | P24723 | 2/20 | 0.37 |
| ▸ | PRKCI | P41743 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14546929 | 1.00 | CA2 (0.50) | CA2CES2THRBGMNNTP53 | |
| SCHEMBL27418490 | 0.92 | CA2 (0.52) | CA2CES2THRBGMNNTP53 | |
| SCHEMBL9231868 | 0.90 | CA2 (0.50) | CA2CES2THRBGMNNTP53 | |
| SCHEMBL14471328 | 0.89 | CA2 (0.38) | CA2CES2THRBGMNNTP53 | |
| SCHEMBL5235323 | 0.89 | — | — | |
| SCHEMBL9231789 | 0.89 | CA2 (0.38) | CA2CES2THRBGMNNTP53 | |
| SCHEMBL9231791 | 0.89 | CA2 (0.38) | CA2CES2THRBGMNNTP53 | |
| SCHEMBL9662709 | 0.89 | CES2 (0.54) | CA2CES2THRBGMNNTP53 | |
| SCHEMBL6424655 | 0.89 | CES2 (0.54) | CA2CES2THRBGMNNTP53 | |
| SCHEMBL11596530 | 0.89 | CES2 (0.54) | CA2CES2THRBGMNNTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394891-B2 | Additive for polymerizable composition, polymerizable composition containing the same and use of the polymerizable composition | MITSUI CHEMICALS, INC. (JP) | 2013-03-12 | — | — | US | disclosed |