SCHEMBL469386

SCHEMBL469386

O=CNc1ccc(NC=O)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.72
LMNA P02545 1/20 0.54
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
LIMK1 P53667 2/20 0.33
TSHR P16473 1/20 0.33
KDM5A P29375 2/20 0.32
MAPT P10636 2/20 0.32
ALOX12 P18054 2/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
PABPC1 P11940 1/20 0.32
CCNE2 O96020 1/20 0.32
CDK4 P11802 1/20 0.32
CCND1 P24385 1/20 0.32
CCNE1 P24864 1/20 0.32
CDK2 P24941 1/20 0.32
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
ADH1B P00325 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9472659 0.88 ALDH1A1 (0.59) ALDH1A1LMNAKMT2AMEN1LIMK1
SCHEMBL90440 0.86 ALDH1A1 (0.56) ALDH1A1LMNAKMT2AMEN1TSHR
SCHEMBL428217 0.86 ALDH1A1 (0.56) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL840514 0.86 ALDH1A1 (0.56) ALDH1A1LMNAKMT2AMEN1
SCHEMBL1747944 0.86 ALDH1A1 (0.56) ALDH1A1LMNAKMT2AMEN1
SCHEMBL14605366 0.86 ALDH1A1 (0.56) ALDH1A1LMNAKMT2AMEN1
SCHEMBL515529 0.86 ALDH1A1 (0.56) ALDH1A1LMNAKMT2AMEN1TSHR
SCHEMBL4457780 0.86 ALDH1A1 (0.56) ALDH1A1LMNAKMT2AMEN1
SCHEMBL8358411 0.86 ALDH1A1 (0.56) ALDH1A1LMNAKMT2AMEN1
SCHEMBL393991 0.86 ALDH1A1 (0.56) ALDH1A1LMNAKMT2AMEN1LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107983385-A A kind of nickel radical magnetic composite materials and its synthetic method and application 渤海大学 2018-05-04 CN claimed
US-5238909-A For preemergence or postemergence use EASTMAN KODAK COMPANY (US) 1993-08-24 US claimed
EP-0476760-A2 4-substituted isoxazole herbicides EASTMAN KODAK COMPANY (US) 1992-03-25 EP claimed
WO-2023010876-A1 ARAMID NANO-AEROGEL FIBER HYDROPHOBICALLY MODIFIED IN SITU, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国科学院苏州纳米技术与纳米仿生研究所 2023-02-09 WO disclosed
CN-114599733-A Antenna system comprising polymer composition with low dissipation factor 提克纳有限责任公司 2022-06-07 CN disclosed
WO-2021025903-A1 NON-COORDINATING ANION TYPE ACTIVATORS FOR USE WITH POLYOLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-02-11 WO disclosed
CN-107983385-A A kind of nickel radical magnetic composite materials and its synthetic method and application 渤海大学 2018-05-04 CN disclosed
CN-107698624-A A kind of application of multi-functional nickel complex based on organic ligand and its method and carbon paste electrode for synthesizing carbon paste electrode 渤海大学 2018-02-16 CN disclosed
CN-103923072-B As the substituted indazole derivative with kinase inhibitory activity 内尔维阿诺医学科学有限公司 2017-05-31 CN disclosed
WO-2016168637-A2 CYCLOPENTA[D]PYRIMIDINES AND SUBSTITUTED CYCLOPENTA[D]PYRIMIDINES AS ANTITUBULIN AND MICROTUBULE TARGETING AGENTS, MONOCYCLIC PYRIMIDINES AS TUBULIN INHIBITORS, AND PYRROLOPYRIMIDINES AS TARGETED ANTIFOLATES AND TUBULIN AND MULTIPLE RECEPTOR TYROSINE KINASE INHIBITION AND ANTITUMOR AGENTS DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) 2016-10-20 WO disclosed
CN-103562782-B The manufacture method of aligning agent for liquid crystal, liquid crystal orientation film, liquid crystal display cells and liquid crystal display cells 日产化学工业株式会社 2016-06-15 CN disclosed
US-5629394-A ENDCAPPING ADDITION POLYMERS WITH NITROGEN FUNCTIONAL GROUPS WHICH CAN BE FURTHER DERIVATIZED EXXON CHEMICAL PATENTS INC (US) 1997-05-13 US disclosed
US-5444135-A Polymerization and functionalization with nitrogen-containing functional groups occur simultaneously EXXON CHEMICAL PATENTS INC. (US) 1995-08-22 US disclosed
US-5336745-A Terminally-substituted polymeric compositions from cationically polymerizable monomers and initiators EXXON CHEMICAL PATENTS INC. (US) 1994-08-09 US disclosed
US-5238909-A For preemergence or postemergence use EASTMAN KODAK COMPANY (US) 1993-08-24 US disclosed
EP-0476760-A2 4-substituted isoxazole herbicides EASTMAN KODAK COMPANY (US) 1992-03-25 EP disclosed
US-5032653-A Catalysts EXXON CHEMICAL PATENTS, INC. (US) 1991-07-16 US disclosed
EP-0349195-A2 Direct synthesis by cationic polymerization of nitrogen-containing polymers EXXON CHEMICAL PATENTS INC. (US) 1990-01-03 EP disclosed
EP-0069494-B1 CATALYTIC SYNTHESIS OF CYCLIC CARBONATES THE STANDARD OIL COMPANY (US) 1985-08-14 EP disclosed
EP-0069494-A1 Catalytic synthesis of cyclic carbonates THE STANDARD OIL COMPANY (US) 1983-01-12 EP disclosed