Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12164785 | 0.89 | LMNA (0.73) | LMNAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL12599371 | 0.85 | KMT2A (0.77) | LMNAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL12164773 | 0.84 | LMNA (0.73) | LMNAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL4666943 | 0.84 | LMNA (0.73) | LMNAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL12599740 | 0.82 | LMNA (0.70) | LMNAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL12164774 | 0.81 | LMNA (0.69) | LMNAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL12164780 | 0.81 | LMNA (0.78) | LMNAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL1616778 | 0.81 | ALDH1A1 (0.71) | LMNAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL10316455 | 0.80 | LMNA (0.91) | LMNAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL1616412 | 0.77 | LMNA (0.76) | LMNAKMT2AMEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394835-B2 | Aromatic compounds and their use in medical applications | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2013-03-12 | — | — | US | disclosed |