SCHEMBL14765692

SCHEMBL14765692

CCOc1ccc(-c2ccc(/C=C/C3CCC(c4ccc(OCC)c(F)c4F)CC3)c(F)c2F)cc1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 2/20 0.31
FFAR4 Q5NUL3 1/20 0.31
ALOX5AP P20292 1/20 0.30
FEN1 P39748 1/20 0.30
FGFR1 P11362 1/20 0.30
FGFR2 P21802 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766686 1.00 FPR2 (0.31) FPR2FFAR4ALOX5APFEN1FGFR1
SCHEMBL14765900 0.94 CHRM2 (0.32) FFAR4
SCHEMBL14766886 0.94 CHRM2 (0.32) FFAR4
SCHEMBL12822926 0.94 FPR2 (0.34) FPR2ALOX5APFEN1
SCHEMBL12718051 0.94 FPR2 (0.34) FPR2ALOX5APFEN1
SCHEMBL14765699 0.93 GYS1 (0.31)
SCHEMBL14766316 0.93 GYS1 (0.31)
SCHEMBL12734233 0.92 ALOX5AP (0.32) FPR2ALOX5APFEN1FGFR1FGFR2
SCHEMBL12739173 0.92 ALOX5AP (0.32) FPR2ALOX5APFEN1FGFR1FGFR2
SCHEMBL14766564 0.91 CHRM2 (0.33) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed