SCHEMBL14765707

SCHEMBL14765707

CCCCOc1ccc(-c2ccc(/C=C/c3ccc(C4CCC(OCCC)CC4)c(F)c3F)cc2)cc1F

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.33
NAAA Q02083 2/20 0.33
HRH3 Q9Y5N1 1/20 0.33
SCN9A Q15858 1/20 0.32
RARA P10276 1/20 0.32
RARB P10826 1/20 0.32
AHR P35869 1/20 0.30
TUBB1 Q9H4B7 1/20 0.30
FFAR1 O14842 1/20 0.30
PPARG P37231 1/20 0.30
PPARD Q03181 1/20 0.30
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14765706 0.97 S1PR1 (0.33) S1PR1NAAAHRH3SCN9ARARA
SCHEMBL14765858 0.95 NAAA (0.35) S1PR1NAAAHRH3SCN9ARARA
SCHEMBL14765742 0.92 S1PR1 (0.31) S1PR1NAAAHRH3SCN9A
SCHEMBL14765868 0.92 SCN9A (0.31) S1PR1NAAAHRH3SCN9A
SCHEMBL12734455 0.90 S1PR1 (0.34) S1PR1HRH3SCN9ARARARARB
SCHEMBL14765703 0.90 NAAA (0.38) NAAAHRH3TUBB1FFAR1PPARG
SCHEMBL14765909 0.88 FPR2 (0.30)
SCHEMBL14766372 0.88 FPR2 (0.30)
SCHEMBL12734460 0.87 FPR2 (0.34) S1PR1HRH3SCN9ARARARARB
SCHEMBL12734469 0.86 PTPN11 (0.33) S1PR1HRH3SCN9ARARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed