Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 3/20 | 0.34 |
| ▸ | ATP4B | P51164 | 3/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765961 | 0.96 | AHR (0.38) | AHRRARARARBS1PR1CNR2 | |
| SCHEMBL14765873 | 0.93 | AHR (0.43) | AHRRARARARBS1PR1HDAC8 | |
| SCHEMBL14765972 | 0.92 | AHR (0.39) | AHRCNR2HDAC8MEN1KMT2A | |
| SCHEMBL14766665 | 0.92 | AHR (0.39) | AHRCNR2HDAC8MEN1KMT2A | |
| SCHEMBL14765956 | 0.92 | FFAR1 (0.38) | AHRMEN1KMT2AFFAR1PPARG | |
| SCHEMBL14766126 | 0.91 | TUBB4A (0.41) | AHRRARARARBS1PR1HDAC8 | |
| SCHEMBL14765761 | 0.91 | AHR (0.41) | AHRRARARARBS1PR1HDAC8 | |
| SCHEMBL14766538 | 0.90 | AHR (0.42) | AHRCNR2MEN1KMT2AFFAR1 | |
| SCHEMBL12734721 | 0.90 | NFE2L2 (0.37) | S1PR1TUBB1 | |
| SCHEMBL14765968 | 0.89 | AHR (0.39) | AHRCNR2HDAC8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |