Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765676 | 0.97 | SCN9A (0.34) | SCN9AGABRA1GABRB2CNR2HTR1D | |
| SCHEMBL14765964 | 0.94 | SCN9A (0.33) | SCN9ACNR2 | |
| SCHEMBL14766808 | 0.94 | SCN9A (0.33) | SCN9ACNR2 | |
| SCHEMBL14766254 | 0.93 | SCN9A (0.32) | SCN9AGABRA1GABRB2CNR2 | |
| SCHEMBL14766854 | 0.93 | SCN9A (0.32) | SCN9AGABRA1GABRB2CNR2 | |
| SCHEMBL14765673 | 0.92 | GABRA1 (0.33) | SCN9AGABRA1GABRB2HCRTR2 | |
| SCHEMBL14766530 | 0.91 | CNR2 (0.32) | SCN9AGABRA1GABRB2CNR2 | |
| SCHEMBL14766689 | 0.91 | CNR2 (0.32) | SCN9AGABRA1GABRB2CNR2 | |
| SCHEMBL14766048 | 0.90 | SCN9A (0.36) | SCN9AGABRA1GABRB2CNR2 | |
| SCHEMBL14766717 | 0.90 | GABRA1 (0.32) | SCN9AGABRA1GABRB2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305627-B1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC CORP (JP) | 2014-09-17 | — | — | EP | disclosed |
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |