Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766939 | 0.93 | LRRK2 (0.33) | HCRTR2ACACBHTR2CHTR2BSCN9A | |
| SCHEMBL14766031 | 0.93 | LRRK2 (0.33) | HCRTR2ACACBHTR2CHTR2BSCN9A | |
| SCHEMBL14765880 | 0.92 | GABRA1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL14766987 | 0.92 | GABRA1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL14765755 | 0.92 | SCN9A (0.36) | GABRA1GABRB2HCRTR2SCN9A | |
| SCHEMBL14765683 | 0.89 | KDM1A (0.39) | GABRA1GABRB2HCRTR2SCN9A | |
| SCHEMBL12733641 | 0.88 | KDM4E (0.36) | KDM4EHTR2CHTR2BSCN9A | |
| SCHEMBL14765795 | 0.88 | HTR2C (0.41) | HCRTR2KDM4EHTR2CHTR2B | |
| SCHEMBL14766757 | 0.88 | HPGD (0.37) | HCRTR2KDM4EACACBSCN9A | |
| SCHEMBL14765893 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305627-B1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC CORP (JP) | 2014-09-17 | — | — | EP | disclosed |
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |