Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | SI | P14410 | 3/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766963 | 0.94 | HTR2C (0.34) | HTR2CHTR2BNPC1POLBMAPT | |
| SCHEMBL14766089 | 0.94 | HTR2C (0.34) | HTR2CHTR2BNPC1POLBMAPT | |
| SCHEMBL14766471 | 0.91 | GYS1 (0.34) | HTR2CHTR2BNPC1POLBMAPT | |
| SCHEMBL14766413 | 0.91 | GYS1 (0.34) | HTR2CHTR2BNPC1POLBMAPT | |
| SCHEMBL14765699 | 0.91 | GYS1 (0.31) | HTR2CHTR2BNPC1POLBMAPT | |
| SCHEMBL14766316 | 0.91 | GYS1 (0.31) | HTR2CHTR2BNPC1POLBMAPT | |
| SCHEMBL14765838 | 0.90 | KDM1A (0.37) | HTR2CHTR2BGYS1HTR2ALMNA | |
| SCHEMBL14767122 | 0.90 | JAK1 (0.36) | NPC1POLBMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL14766661 | 0.90 | JAK1 (0.36) | NPC1POLBMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL14766603 | 0.90 | CTSL (0.32) | HTR2CHTR2BGYS1HTR2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |